id: sig-20260710-msk-mechanism
site_id: musculoskeletal-syndrome-menopause
site_hint: "Joint and muscle pain (musculoskeletal syndrome of menopause) — symptom"
attribute: mechanism
value: "Supporting estrogen's role: aromatase inhibitors, which sharply lower estrogen, cause new or worsening joint pain in roughly half of women who take them."
source_url: https://pubmed.ncbi.nlm.nih.gov/39077777/
source_title: "Musculoskeletal syndrome of menopause (Climacteric 2024, PMID 39077777)"
publisher: Climacteric
source_date: "2024"
observed_date: "2026-07-10"
collected_by: gn_info_scout/1.0.0
confidence: high